Caffeine augmentation of electroconvulsive seizures
نویسندگان
چکیده
منابع مشابه
Effectiveness of Electroconvulsive Therapy Augmentation on Clozapine-Resistant Schizophrenia
OBJECTIVE This retrospective case series study of the effectiveness of electroconvulsive therapy (ECT) augmentation on clozapine-resistant schizophrenia was conducted by EMR review. METHODS Clozapine-resistance was defined as persistent psychotic symptoms despite at least 12 weeks of clozapine administration with blood levels over 350 ng/mL in order to rule out pseudo-resistance. Seven in-pat...
متن کاملElectroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways.
Electroconvulsive therapy (ECT) remains the treatment of choice for drug-resistant patients with depressive disorders, yet the mechanism for its efficacy remains unknown. Gene transcription changes were measured in the frontal cortex and hippocampus of rats subjected to sham seizures or to 1 or 10 electroconvulsive seizures (ECS), a model of ECT. Among the 3500-4400 RNA sequences detected in ea...
متن کاملElectroconvulsive seizures induce endothelial cell proliferation in adult rat hippocampus.
BACKGROUND Electroconvulsive seizures, an animal model for electroconvulsive treatment, induce a strong increase in neurogenesis in the dentate gyrus of adult rats. Hippocampal neurogenesis has previously been described as occurring in an angiogenic niche. This study examines the effect of electroconvulsive seizures on proliferation of vascular cells in rat hippocampus. METHODS Rats were inje...
متن کاملElectroconvulsive seizures increase hippocampal neurogenesis after chronic corticosterone treatment.
Major depression is often associated with elevated glucocorticoid levels. High levels of glucocorticoids reduce neurogenesis in the adult rat hippocampus. Electroconvulsive seizures (ECS) can enhance neurogenesis, and we investigated the effects of ECS in rats where glucocorticoid levels were elevated in order to mimic conditions seen in depression. Rats given injections of corticosterone or ve...
متن کاملHippocampal Neurons Are Damaged Augmented Electroshock Seizures by Caffeine-
Caffeine-augmented electroconvulsive therapy has been introduced into medical practice without experimental confirmation that such seizure modification does not result in neuronal injury. In this report rats pretreated with caffeine prior to a series of nine electrically induced convulsions showed neuronal injury confined to hippocampal sectors and striatum. Electrically induced convulsions wit...
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ژورنال
عنوان ژورنال: Psychopharmacology
سال: 1994
ISSN: 0033-3158,1432-2072
DOI: 10.1007/bf02244884